From RCT into NNT
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From pre-test probability into post-test probability
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The Cochrane Library
"Clinical Evidence" OnLine
"Evidence-Based Medicine" Online
"Evidence-Based Mental Health" OnLine
PubMed
... and more
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Clinical problems awaiting solution
Clinical problems for which we found no evidence to act upon. If you know of any good evidence, please write us at webmaster@ebpcenter.com.

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Patients Major depression
Exposure Milnacipran 100 mg/d
Comparison Milnacipran 50 mg/d
Outcome "Excellent or good" global assessment within 4 weeks
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Patients Patients with depression on continuation/maintenance treatment
Exposure 2 home visits by a specialist and 3 telephone calls over one year, in addition to treatment as usual by a primary care physic
Comparison Treatment as usual by a primary care physician
Outcome Better drug compliance, less depression but not fewer relapse/recurrence
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Patients Inpatients with bipolar disorder or major depression
Exposure Psychoeducational family intervention aiming at acceptance of disease, identification of precipitators and family interaction
Comparison Treatment as usual
Outcome Global Assessment Scale and many others
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Patients Patients with bipolar disorder, manic episode
Exposure valproate
Comparison placebo
Outcome Mania Rating Scale
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Patients Schizophrenia, refractory
Exposure ECT
Comparison @
Outcome @
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Patients Schizophrenia
Exposure Antipsychotics
Comparison @
Outcome Teratogenecity
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Patients Delusional depression
Exposure Amitriptyline 100-200 mg/day + perphenazine 32-64 mg/day
Comparison Amitriptyline 150-250 mg/day
Outcome No delusion & HRSD<6
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Patients Delusional depression
Exposure ECT
Comparison Antidepressant+antipsychotic
Outcome @
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Patients Depression
Exposure Amitriptyline 75 mg or mianserin 30 mg h.s.
Comparison Amitriptyline 25 mg or mianserin 10 mg t.i.d.
Outcome Compliance at 6 weeks (self-report)
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Patients Depression
Exposure Patient's choice (Amitriptyline 75 mg or mianserin 30 mg h.s. OR amitriptyline 25 mg or mianserin 10 mg t.i.d.)
Comparison Amitriptyline 25 mg or mianserin 10 mg t.i.d.
Outcome Compliance at 6 weeks (self-report)
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Showing records 1-10 of 16
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Dept of Psychiatry and Cognitive-Behavioral Medicne,
Nagoya City University Graduate School of Medical Sciences
Mizuho-cho, Mizuho-ku,
Nagoya 467-8601 JAPAN
Phone: +81-52-853-8271
Fax: +81-52-852-0837



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