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| Clinical problems awaiting solution |
| Clinical problems for which we found no evidence to act upon. If you know of any good evidence, please write us at webmaster@ebpcenter.com. |
| Category |
Treatment
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| Patients |
Depression |
| Exposure |
Patient's choice (Amitriptyline 75 mg or mianserin 30 mg h.s. OR amitriptyline 25 mg or mianserin 10 mg t.i.d.) |
| Comparison |
Amitriptyline 25 mg or mianserin 10 mg t.i.d. |
| Outcome |
Compliance at 6 weeks (self-report) |
| EER |
0.58 |
| CER |
0.54 |
| NNT/NNH |
RR=1.1 (0.7 to 1.7) |
| Comments |
The confidence interval is too wide to exclude clinically meaningful benefit.@ |
| Reference |
Myers, E. D. & Branthwaite, A. (1992). Out-patient compliance with antidepressant medication. British Journal of Psychiatry 160, 83-86.
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| Appraiser |
@ |
| Lastappraised |
@ |
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From RCT into NNT
