From RCT into NNT From ES into NNT From RR  into NNT From OR  into NNT From diagnostic study into LR/SSLR From pre-test probability into post-test probability ... and more

The Cochrane Library "Clinical Evidence" OnLine "Evidence-Based Medicine" Online "Evidence-Based Mental Health" OnLine PubMed ... and more

The Cochrane Library "Clinical Evidence" OnLine "Evidence-Based Medicine" Online "Evidence-Based Mental Health" OnLine PubMed ... and more

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		Clinical problems awaiting solution Clinical problems for which we found no evidence to act upon. If you know of any good evidence, please write us at webmaster@ebpcenter.com. Category Treatment Patients Delusional depression Exposure Amitriptyline 100-200 mg/day + perphenazine 32-64 mg/day Comparison Amitriptyline 150-250 mg/day Outcome No delusion & HRSD<6 EER 0.64 CER 0.47 NNT/NNH NNT=6.2 (ns) Comments The only RCT to recommend combination therapy was no longer significant if analyzed on an ITT basis! Reference Spiker DG et al (1985). The pharmacological treatment of delusional depression. American Journal of Psychiatry 142, 430-436. Appraiser Dr Takahiro Kamao Lastappraised 1/30/2003
Dept of Psychiatry and Cognitive-Behavioral Medicne, Nagoya City University Graduate School of Medical Sciences Mizuho-cho, Mizuho-ku, Nagoya 467-8601 JAPAN Phone: +81-52-853-8271 Fax: +81-52-852-0837

| HOME | Awaiting | Spreadsheets | Links | (c)1999-2006 Dept of Psychiatry and Cognitive-Behavioral Medicine, Nagoya City University Graduate School of Medical Sciences